Genetic variants affecting incretin sensitivity and incretin secretion
نویسندگان
چکیده
منابع مشابه
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion.
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are incretins secreted in response to oral glucose ingestion by intestinal L and K cells, respectively. The molecular mechanisms responsible for intestinal cell glucose sensing are unknown but could be related to those described for beta-cells, brain and hepatoportal sensors. We determined the role of GLUT2, ...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2010
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-010-1876-8